Indications and usage of Medrol
Systemic connective tissue diseases (SLE, scleroderma, periarteritis nodosa, dermatomyositis, rheumatoid arthritis). Acute and chronic inflammatory diseases of the joints: gouty and psoriatic arthritis, osteoarthritis (including post-traumatic), polyarthritis, humeroscapular periarthritis, ankylosing spondylitis (Bekhterev’s disease), juvenile arthritis, Still’s syndrome in adults, bursitis, nonspecific tendosynovitis, synovitis and epicondylitis . Rheumatic fever, acute rheumatic fever. Bronchial asthma, status asthmaticus. Acute and chronic allergic diseases: allergic reactions to drugs and food, serum sickness, urticaria, allergic rhinitis, angioedema, drug exanthema, hay fever. Allergic eye diseases: allergic corneal ulcers, allergic forms of conjunctivitis. Skin diseases: pemphigus, psoriasis, eczema, atopic dermatitis, diffuse neurodermatitis, contact dermatitis (with damage to a large surface of the skin), toxidermia, seborrheic dermatitis, exfoliative dermatitis, toxic epidermal necrolysis (Lyell’s syndrome), bullous dermatitis herpetiformis, malignant exudative erythema (syndrome Stevens-Johnson). Cerebral edema (including against the background of a brain tumor or associated with surgery, radiation therapy or head trauma) after preliminary parenteral use. Inflammatory eye diseases: sympathetic ophthalmia, severe sluggish anterior and posterior uveitis, optic neuritis. Primary or secondary adrenal insufficiency (including condition after removal of the adrenal glands). Congenital adrenal hyperplasia. Kidney diseases of autoimmune origin (including acute glomerulonephritis); nephrotic syndrome. Subacute thyroiditis. Diseases of the hematopoietic organs: agranulocytosis, panmyelopathy, autoimmune hemolytic anemia, acute lympho- and myeloid leukemia, lymphogranulomatosis, thrombocytopenic purpura, secondary thrombocytopenia in adults, erythroblastopenia (erythrocyte anemia), congenital (erythroid) hypoplastic anemia. Lung diseases: acute alveolitis, pulmonary fibrosis, sarcoidosis II-III stage. Tuberculous meningitis, pulmonary tuberculosis, aspiration pneumonia (in combination with specific chemotherapy). Berilliosis, Leffler’s syndrome (not amenable to other therapy). Lung cancer (in combination with cytostatics). Multiple sclerosis. Gastrointestinal diseases: ulcerative colitis, Crohn’s disease, local enteritis. Hepatitis. Prevention of graft rejection. Hypercalcemia against the background of oncological diseases, nausea and vomiting during cytostatic therapy. Myeloma.
Contraindications Medrol
For short-term use for “vital” indications – hypersensitivity to methylprednisolone. With caution. Parasitic and infectious diseases of a viral, fungal or bacterial nature (currently or recently transferred, including recent contact with a patient): herpes simplex, herpes zoster (viremic phase), chicken pox, measles; amoebiasis, strongyloidiasis (established or suspected); systemic mycosis; active and latent tuberculosis. Use in severe infectious diseases is permissible only against the background of specific therapy. Post-vaccination period (period lasting 8 weeks before and 2 weeks after vaccination), lymphadenitis after BCG vaccination. Immunodeficiency states (including AIDS or HIV infection). Gastrointestinal diseases: peptic ulcer of the stomach and duodenum, esophagitis, gastritis, acute or latent peptic ulcer, recently created intestinal anastomosis, ulcerative colitis with the threat of perforation or abscess formation, diverticulitis. Diseases of the cardiovascular system, incl. recent myocardial infarction (in patients with acute and subacute myocardial infarction, a focus of necrosis may spread, a slowdown in the formation of scar tissue, and as a result, rupture of the heart muscle), decompensated CHF, arterial hypertension, hyperlipidemia). Endocrine diseases: diabetes mellitus (including impaired carbohydrate tolerance), thyrotoxicosis, hypothyroidism, Itsenko-Cushing’s disease. Severe chronic renal and / or liver failure, nephrourolithiasis. Hypoalbuminemia and conditions predisposing to its occurrence. Systemic osteoporosis, myasthenia gravis, acute psychosis, obesity (III-IV stage), poliomyelitis (except for the form of bulbar encephalitis), open and angle-closure glaucoma, pregnancy, lactation.
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