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Transplantation of leading organs:
prevention of rejection of kidney, liver, heart, lung, pancreas allografts, as well as combined cardiopulmonary transplant;
treatment of transplant rejection in patients previously treated with other immunosuppressants.
Bone marrow transplantation
prevention of graft rejection after bone marrow transplant;
prevention and treatment of graft-versus-host disease” (TPH).
Indications not related to transplantation
Endogenous uveitis
active sight-threatening middle or posterior uveitis of non-infectious etiology in cases where traditional treatment has not had an effect or in cases of severe side effects;
Behcet’s uveitis with repeated attacks of inflammation involving the retina.
Nephrotic syndrome
steroid-dependent and steroid-resistant nephrotic syndrome in adults and children, caused by glomerular pathology, such as minimal change nephropathy, focal and segmental glomerulosclerosis, membranous glomerulonephritis. The drug Sandimmune® Neoral® can be used to induce and maintain remission. It can also be used to maintain remission caused by GCS, which allows them to be canceled.
Rheumatoid arthritis
treatment of severe forms of active rheumatoid arthritis.
Psoriasis
treatment of severe forms of psoriasis when traditional therapy is ineffective or impossible.
Atopic dermatitis
severe forms of atopic dermatitis, when systemic therapy is required.
Hypersensitivity (including to polyoxyethylene castor oil – for dosage forms containing it); malignant neoplasms, precancerous skin diseases; children’s age (up to 1 year), lactation period, childhood (for use in the treatment of psoriasis and rheumatoid arthritis).
With caution. Varicella zoster (risk of generalization of the process) and other viral diseases, renal and/or liver failure, hyperkalemia, arterial hypertension, infections, malabsorption syndrome.
Hypersensitivity; malignant neoplasms, precancerous skin diseases; children’s age (up to 1 year), lactation period, childhood (for use in the treatment of psoriasis and rheumatoid arthritis). With caution. Chicken pox (currently or recently, including recent contact with a patient), Varicella zoster (risk of generalization of the process) and other viral diseases, renal and/or liver failure, hyperkalemia, arterial hypertension, infections, malabsorption syndrome.
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