Pharmacological action – estrogenic.
Pharmachologic effect
Pharmacological action – estrogenic.
Compensates for the insufficient production of endogenous estrogens, lowers the level of LDL cholesterol in the blood. Relieves somatic, mental and other menopausal symptoms during pre- and postmenopause or after oophorectomy; prevents bone loss and osteoporosis.
Indications
Estrogen deficiency (postmenopausal period, oophorectomy, radiation castration), accompanied by vasomotor symptoms: hot flashes, sweating, sleep disturbance, depression, irritability, headache, dizziness, bladder hyperesthesia, degenerative changes in the skin and mucous membranes; prevention of osteoporosis.
Contraindications
Hypersensitivity, pregnancy, lactation, severe liver dysfunction, Dubin-Johnson and Rotor syndromes, liver tumors and thromboembolic processes (including history), breast cancer, existing or suspected tumors sensitive to sex steroid hormones, severe hypertriglyceridemia, vaginal bleeding of unknown origin.
Use during pregnancy and lactation
Contraindicated in pregnancy. At the time of treatment should stop breastfeeding.
Original
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